Effects of certain natural products against lipopolysaccharide- induced hepatotoxicity in rats

Abstract

Liver diseases and particularly hepatotoxicity are now receiving a supreme importance; due to the large population suffering of hepatic disorders all over the world. From the attempts to use the natural products to the intense use of drugs the patients are out there waiting the expected help so as to be well again. Depending on a wide research bases and a powerful huge advance in the medical field technology, hundreds of studies are made yearly for developing the art of using both the natural and the synthetic agents to enhance and enlarge the agents available to be used in such conditions. So, the current study is focusing on the use of the in-vitro method for the purpose of providing a new important tool to be added along the well documented and trusted studies to help minimizing the suffering of the patients especially that the use of that kind of studies could enable the researchers of the vast and wide screening of the new promising compounds, we thought in a new natural product to be screened. Liver toxicity could be induced in the expermintal field by usage of either chemicals such as (CCl4, Alcohol) or biologically such as the use of (LPS), and the models used could be in-vivo, in-vitro in addition to the ex-vivo.