Preferred Name

Mild hyperpolarizing shift of voltage dependence of activation

Synonyms
Definitions

SCN2A and SCN8A mild: up to 5 mV; K+ channels mild: up to 10mV Gain-of-function

ID

http://webprotege.stanford.edu/R8asTBmmgK6PYqOlvlLtgpz

comment

SCN2A and SCN8A mild: up to 5 mV; K+ channels mild: up to 10mV

Gain-of-function

definition

A mild hyperpolarizing shift of voltage dependence of activation is a hyperpolarizing shift of voltage dependence of activation (left shift) of a voltage-gated ion channel in which the value of V1/2 is significantly decreased by up to 5mV for Na+ channels or 10mV for K+ channels.

label

Mild hyperpolarizing shift of voltage dependence of activation

prefixIRI

webprotege:R8asTBmmgK6PYqOlvlLtgpz

prefLabel

Mild hyperpolarizing shift of voltage dependence of activation

rdfs:ID

FENICS:0029

subClassOf

http://webprotege.stanford.edu/Rl7K1Hgqs34BVxM4PNtn4w

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