Functional Electrophysiology Nomenclature for Ion Channels

Last uploaded: November 23, 2021

Preferred Name	Moderate hyperpolarizing shift of voltage dependence of activation
Synonyms
Definitions	SCN2A and SCN8A moderate: 5-10 mV shift Gain-of-function
ID	http://webprotege.stanford.edu/R8LYDXXexzlysXjoPyjBePm
comment	SCN2A and SCN8A moderate: 5-10 mV shift Gain-of-function
definition	A moderate hyperpolarizing shift of voltage dependence of activation is a hyperpolarizing shift of voltage dependence of activation (left shift) of a voltage-gated ion channel in which the value of V1/2 is significantly decreased by 5-10mV for Na+ channels or 10-20mV for K+ channels.
label	Moderate hyperpolarizing shift of voltage dependence of activation
prefixIRI	webprotege:R8LYDXXexzlysXjoPyjBePm
prefLabel	Moderate hyperpolarizing shift of voltage dependence of activation
rdfs:ID	FENICS:0030
subClassOf	http://webprotege.stanford.edu/Rl7K1Hgqs34BVxM4PNtn4w

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